The episode’s title refers to the defining plot reveal. For years within the series, the Ope Ope no Mi was considered the "Ultimate Devil Fruit." Episode 722 finally explains why.
Zoro lowers Wado Ichimonji. “Killer. I don’t know what they did to you. But I remember the man who laughed at a banquet with his captain. I won’t kill you.” One Piece Episode 722
Notably, Luffy is almost absent from the emotional geography of this episode. He exists only as a force—a rubber fist breaking the ceiling of the royal plateau. This is deliberate. Episode 722 suggests that Luffy is not a hero in the traditional sense; he does not give speeches or demand gratitude. He simply destroys the source of pain. The liberation of Dressrosa is a side effect of his hunger for freedom. The episode’s title refers to the defining plot reveal
The "core" mentioned in the title refers specifically to the —the massive factory producing artificial Zoan Devil Fruits for Kaido. The strategy is simple: Destroy the factory, and Doflamingo loses his bargaining chip with the Emperors of the Sea. “Killer